PuraPly AM is supplied in an individually sealed dry sheet and packaged in a sterile, sealed single pouches. PuraPly AM offers convenient room temperature storage and comes in the following sizes to manage a wide variety of wound types.1,2

Product CodeProduct Description/Size
PURAPLYAM-COM 2X22cm x 2cm
PURAPLYAM-COM 2X42cm x 4cm
PURAPLYAM-COM 5X55cm x 5cm
PURAPLYAM-COM 6X96cm x 9cm
PURAPLYAM-COM 8X168cm x 16cm

Do not freeze or expose PuraPly AM to excessive heat.


PuraPly AM consists of a collagen sheet coated with 0.1% polyhexamethylenebiguanide hydrochloride (PHMB) intended for the management of wounds.


Do not re-sterilize. The device is intended for single patient use only. Do not reuse. Discard all open and unused portions. PuraPly AM is sterile if the package is dry, unopened, and undamaged. Do not use if the package seal is broken. PuraPly AM must be used prior to the expiration date. Discard PuraPly AM if mishandling has caused possible damage or contamination. PuraPly AM should not be applied until excessive exudate, bleeding, acute infection, and significant swelling are controlled.

Science Behind Product

PuraPly AM utilizes an inherently strong biocompatible fenestrated sheet of porcine-derived collagen coated with PHMB.3


  • Is a naturally occurring building block that supports healing.4
  • Is the most abundant structural component of the dermal matrix.4


  • Inhibits the reformation of biofilm.3
  • Does not impair wound healing, unlike other antimicrobials.3
  • Has low cytotoxicity and high tissue compatability.3
Clinical Data

Organogenesis has a culture of scientific advancement, a strong commitment to product innovation, and is dedicated to clinical research.

  1. PuraPly Antimicrobial [package insert]. Canton, MA: Organogenesis, Inc; 2015.
  2. Data on file. Organogenesis, Inc.
  3. Hubner NO, Kramer A. Skin Pharmacol Physiol. 2010;23(suppl):17-27.
  4. Brett D. Wounds. 2008;20(12):347-356.

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